Generic Medicines
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USES
Pioglitazone is an anti-diabetic drug (thiazolidinedione-type, also
called "glitazones") used along with a proper diet and exercise program to
control high blood sugar in patients with type 2 diabetes
(non-insulin-dependent diabetes). It works by helping to restore your
body's proper response to insulin, thereby lowering your blood sugar.
Controlling high blood sugar helps prevent kidney damage, blindness, nerve
problems, loss of limbs, and sexual function problems. Proper control of
diabetes may also lessen your risk of a heart attack or
stroke.Pioglitazone is used either alone or in combination with other
anti-diabetic medications (e.g., metformin, sulfonylureas, insulin).
HOW TO USE
Read the Medication Guide provided by your pharmacist before
you start
taking this medication and each time you get a refill. If you have any
questions, consult your doctor or pharmacist.Take this medication by
mouth, with or without food, usually once daily, or as directed by your
doctor. Dosage is based on your medical condition, response to therapy,
and if you are taking other anti-diabetic drugs.Use this medication
regularly in order to get the most benefit from it. Remember to use it at
the same time(s) each day. Monitor blood glucose levels on a regular
basis.It may take up to 2 to 3 months before the full benefit of this drug
takes effect.Take all other medications for diabetes as directed by your
doctor.
SIDE EFFECTS
See also Warning section.Sore throat, muscle pain, or tooth problems
may occur. If any of these effects persist or worsen, notify your doctor
or pharmacist promptly.Remember that your doctor has prescribed this
medication because he or she has judged that the benefit to you is greater
than the risk of side effects. Many people using this medication do not
have serious side effects.Tell your doctor immediately if any of these
unlikely but serious side effects occur: fast/pounding heartbeat, changes
in menstrual cycles, new/worsening vision problems (e.g., color or night
vision problems), bone fracture.Tell your doctor immediately if any of
these highly unlikely but very serious side effects occur: dark urine,
yellowing of eyes/skin, persistent nausea/vomiting, stomach/abdominal
pain.This medication usually does not cause low blood sugar
(hypoglycemia), but this effect may occur if you do not consume enough
calories (from food, juices, fruit, etc.). The symptoms include chills,
cold sweat, dizziness, drowsiness, shaking, rapid heart rate, weakness,
headache, fainting, tingling of the hands or feet, or hunger. It is a good
habit to carry glucose tablets or gel to treat low blood sugar. If you are
in a situation where you don't have these reliable forms of glucose, eat a
quick source of sugar such as table sugar, honey, or candy, or drink a
glass of orange juice or non-diet soda to quickly raise your blood sugar
level. Tell your doctor immediately about the reaction. To help prevent
hypoglycemia, eat meals on a regular schedule and do not skip
meals.Symptoms of high blood sugar (hyperglycemia) include thirst,
increased urination, confusion, drowsiness, flushing, rapid breathing, or
fruity breath odor. If these symptoms occur, tell your doctor immediately.
Your medication dosage may need to be increased.A serious allergic
reaction to this drug is unlikely, but seek immediate medical attention if
it occurs. Symptoms of a serious allergic reaction include: rash,
itching/swelling (especially of the face/tongue/throat), dizziness,
trouble breathing.This is not a complete list of possible side effects. If
you notice other effects not listed above, contact your doctor or
pharmacist.In the US -Call your doctor for medical advice about side
effects. You may report side effects to FDA at 1-800-FDA-1088.In Canada -
Call your doctor for medical advice about side effects. You may report
side effects to Health Canada at 1-866-234-2345.
PRECAUTIONS
Before taking pioglitazone, tell your doctor or pharmacist if you are
allergic to it; if you are allergic to other "glitazones" (e.g.,
rosiglitazone); or if you have any other allergies.This medication should
not be used if you have certain medical conditions. Before using this
medicine, consult your doctor or pharmacist if you have: type 1 diabetes
(insulin-dependent diabetes), newly diagnosed or worsening heart failure
(acute congestive heart failure), very high blood glucose (diabetic
ketoacidosis), active liver disease.Before using this medication, tell
your doctor or pharmacist your medical history, especially of: heart
disease (e.g., chronic congestive heart failure), liver problems, fluid in
your lungs, swelling (edema), anemia, eye (retina) problems.You may
experience blurred vision, dizziness, or drowsiness due to extremely low
or high blood sugar levels. Do not drive, use machinery, or do any
activity that requires alertness or clear vision until you are sure you
can perform such activities safely.Limit alcohol while taking this
medication because it can increase the risk of developing
hypoglycemia.During times of stress, such as fever, infection, injury or
surgery, it may be more difficult to control your blood sugar. Consult
your doctor, as a change in your medication may be required.This
medication may increase the risk of bone fracture (e.g., upper arm, hand,
foot, ankle) in female patients. To lower the chance of getting injured,
use caution when doing activities such as contact sports.This medication
can cause changes in the menstrual cycle (ovulation) in women with certain
fertility problems. Consult your doctor or pharmacist about the use of
reliable birth control while taking this medication.This medication should
be used only when clearly needed during pregnancy. Discuss the risks and
benefits with your doctor. Your doctor may substitute insulin for this
drug during your pregnancy. Follow all instructions carefully.It is not
known whether this drug passes into breast milk. Breast-feeding while
using this drug is not recommended. Consult your doctor before
breast-feeding.
DRUG INTERACTIONS
Your healthcare professionals (e.g., doctor or pharmacist) may already
be aware of any possible drug interactions and may be monitoring you for
it. Do not start, stop or change the dosage of any medicine before
checking with them first.Before using this medication, tell your doctor or
pharmacist of all prescription and nonprescription/herbal products you may
use, especially of: other anti-diabetic medications (e.g., insulin,
metformin, or sulfonylureas such as glyburide), herbal/natural products
(e.g., fenugreek, ginseng, gymnema), drugs affecting liver enzymes that
remove pioglitazone from your body (e.g., gemfibrozil, rifamycins
including rifampin), quinolone antibiotics (e.g., ciprofloxacin).This
medication may decrease the effectiveness of birth control pills. This can
result in pregnancy. You may need to use an additional form of reliable
birth control while using this medication. Consult your doctor or
pharmacist for details.Beta-blocker medications (e.g., metoprolol,
propranolol, glaucoma eye drops such as timolol) may prevent the
fast/pounding heartbeat you would usually feel when your blood sugar level
falls too low (hypoglycemia). Other symptoms of low blood sugar such as
dizziness, hunger, or sweating are unaffected by these drugs.This document
does not contain all possible interactions. Therefore, before using this
product, tell your doctor or pharmacist of all the products you use. Keep
a list of all your medications with you, and share the list with your
doctor and pharmacist.
OVERDOSE
If overdose is suspected, contact your local poison control center or
emergency room immediately. US residents can call the US national poison
hotline at 1-800-222-1222. Canadian residents should call their local
poison control center directly.
MISSED DOSE
If you miss a dose, use it as soon as you remember. If it is near the time
of the next dose, skip the missed dose and resume your usual dosing
schedule. Do not double the dose to catch up.
STORAGE
Store at 77 degrees F (25 degrees C) away from light and moisture.
Brief storage between 59-86 degrees F (15-30 degrees C) is permitted. Do
not store in the bathroom. Keep all medicines away from children and
pets.Do not flush medications down the toilet or pour them into a drain
unless instructed to do so. Properly discard this product when it is
expired or no longer needed. Consult your pharmacist or local waste
disposal company for more details about how to safely discard your
product.MEDICAL ALERT: Your condition can cause complications in a medical
emergency. For enrollment information call MedicAlert at 1-800-854-1166
(USA) or 1-800-668-1507 (Canada).
WARNING: This medication may
infrequently cause or worsen a certain heart problem (congestive heart
failure). Tell your doctor immediately if you notice any symptoms of heart
failure, including: swelling of the hands/feet, unusual/sudden weight
gain, trouble breathing, or unusual tiredness.
Note : This product information is intended only for residents of the India. Taj Pharmaceuticals Limited, medicines help to treat and prevent a range of conditions—from the most common to the most challenging—for people around the world.