Cefozone (Cefuroxime Sod. I.P)

Each Injection contians:

Composition:
Sulbactum Sodium USP equivalent to Sulbactam ...........0.5 mg
Cefoperazone Sodium USP
equivalent to Cefoperazone..............................................….0.5 mg

Indications : Cefuroxime is used to treat certain infections caused by bacteria, such as bronchitis; gonorrhea; Lyme disease; and infections of the ears, throat, sinuses, urinary tract, and skin. Cefuroxime is in a class of medications called cephalosporin antibiotics. It works by stopping the growth of bacteria. Antibiotics will not work for colds, flu, or other viral infections.

Description: CEFOZONE a derivative of the basic penicillin nucleus, is a beta-lactamase inhibitor. Chemical designation is (2S, 5R)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0] heptane-2-carboxylate 4,4-dioxide. It is used to increase the antibacterial spectrum of penicillins and cephalosporins against penicillinase-producing and beta-lactamase-producing organisms such as Staphylococcus aureus, H. flu, Moraxella catarrhalis that are resistant to ampicillin alone. Sulbactam does not improve enterococcal activity of ampicillin. Aampicillin/Gentamicin combination is used for the treatment of enterococcal infection. Sultamicillin is the combination of ampicillin and sulbactam. Sultamicillin is a white to off-white crystalline powder; soluble in aqueous diluents to yield reconstitution of ampicillin and sulbactam.

Contraindications: Sulbactam/cefoperazone is contraindicated in patients with known allergy to penicillins, sulbactam, cefoperazone, or any of the cephalosporins in neonates, especially when premature, and other infants.

Dosage : Adults: The usual adult dosage range for Cepokem is 750 mg to 1.5 grams every 8 hours, usually for 5 to 10 days.